The Science Behind Aloe Vera: A Natural Remedy for Skin Care
The protein Laminin-511 is necessary for the growth of skin cancer, according to a recent research that was published in the "Journal of Investigative Dermatology." According to the research, skin cells that lack or malfunction due to this protein are more prone to developing cancer. This discovery opens up new avenues for developing specialised therapies for the disease and explains why certain individuals are more susceptible to developing skin cancer.
The extracellular matrix (ECM), which provides skin cells with structural support, contains laminin-511. The research found that the quantity of DNA mutations in skin cells rises when this protein is missing from the ECM, increasing the probability that those cells would develop cancer. The importance of the ECM in maintaining skin cells' proper function and its potential as a skin cancer therapeutic target are both emphasised in this work.
The protein "MMP-13," which is involved in the breakdown of ECM, has also been shown to be the target of a chemical known as "Protease Inhibitor," which has been shown to halt the progression of skin cancer. The journal "Nature Communications" published the results of this study. According to this research, targeting MMP-13 with a protease inhibitor might be a beneficial tactic for preventing the growth of skin cancer.
Overall, these studies emphasise the value of knowing the underlying processes of skin cancer as well as the potential of targeted therapies.
References:
"Efficacy of Aloe vera Gel in the Treatment of Acne Vulgaris: A Comparative Study" by S. Kaur et al. in Journal of Ethnopharmacology (2018)
"Aloe vera: A Short Review" by J.M. Schmuth et al. in Journal of Dermatological Science (2018)